A high centrifugal force-enhanced Ziehl-Neelsen method for improved detection of Mycobacterium tuberculosis
This study demonstrates that increasing centrifugal force to 6,000 x g during pre-analytical processing significantly enhances the sensitivity of Ziehl-Neelsen smear microscopy for detecting *Mycobacterium tuberculosis* in clinical sputum samples, thereby reducing false-negative results in routine tuberculosis diagnosis.